Dicalcium phosphate is the calcium phosphate with the formula CaHPO4 and its dihydrate. The "di" prefix in the common name arises because the formation of the HPO42– anion involves the removal of two protons from phosphoric acid, H3PO4. It is also known as dibasic calcium phosphate or calcium monohydrogen phosphate. Dicalcium phosphate is used as a food additive, it is found in some toothpastes as a polishing agent and is a biomaterial.
1. Dibasic calcium phosphate is produced by the neutralization of calcium hydroxide with phosphoric acid, which precipitates the dihydrate as a solid. At 60 °C the anhydrous form is precipitated:
H3PO4 + Ca(OH)2 → CaHPO4
To prevent degradation that would form hydroxyapatite, sodium pyrophosphate or trimagnesium phosphate octahydrate are added when for example, dibasic calcium phosphate dihydrate is to be used as a polishing agent in toothpaste.
2. In a continuous process CaCl2 can be treated with (NH4)2HPO4 to form the dihydrate:
CaCl2 + (NH4)2HPO4 → CaHPO4•2H2O
A slurry of the dihydrate is then heated to around 65–70 °C to form anhydrous CaHPO4 as a crystalline precipitate, typically as flat diamondoid crystals, which are suitable for further processing.
This medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).
Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Having the right amount of calcium is important for building and keeping strong bones.
Farmers often supplement their livestock feed with inorganic phosphorus. This technique compensates for the low availability and poor digestibility of food-related phosphorus. A January 2018 report in the Journal of Entomology and Zoology showed that dicalcium phosphate supplementation created high levels of circulating phosphorus. Many people with mineral deficiencies use supplements to give them access to calcium and phosphorus.
Dicalcium phosphate supplementation has other benefits. A February 2015 article in Aquaculture Nutrition showed that young fish given dicalcium phosphate grew into larger, more muscular adults, and scientists have found similar results in many farm animals. Supplementing calcium and phosphorus may also help you prevent age-related bone loss.
Oral surgeons also use dicalcium phosphate to aid in the healing process. A May 2018 article in the Open Dentistry Journal described the positive impact the chemical can have on oral health.
Your body can't tell the difference between dicalcium phosphate and real teeth. Such biomimetics have great potential given their safety profile. Dicalcium phosphate can also replace fluoride as the best way to prevent tooth decay. Manufacturers often add it to teeth whiteners as an abrasive to gently polish your teeth.
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Driven by the idea of providing top-quality Dicalcium phosphate for our customers, we at Tradeasia International aim to organize and offer top-notch Dicalcium phosphate that particularly used in several industries for different purposes.
In the food industry, it is used as a dietary supplement to prepare food like noodles, breakfast cereals and in the improvement of flour.
In the Pharma industry, it is used to prepare tablets like body odor maintainer because of the present tartar controlling agent.
In poultry feed, it is used to improve the strength of the skeleton and stimulates the animal's growth.
It is also used as a polishing agent after heating.